The Neurovascular Research Unit (UIN), integrated in the Department of Pharmacology of the Faculty of Medicine of the UCM, is coordinated by Professor Ignacio Lizasoain (University Professor). The Unit is made up of another Professor, two Senior Lecturers, a Lecturer and a manager. The UIN is forged with a two-pronged approach, teaching and research. As part of a University Department, a cardinal objective of the Unit is to train future teachers and researchers, and contribute to the generation of new knowledge. In its research aspect, the UIN focuses on the research of neurovascular pathology from a basic point of view and with a strong translational projection. Another of UIN's aims is to generate results that can be transferred to industry and improve our country's capacity for innovation.
Within the neurovascular pathology, the main lines developed in the UIN are the following: i) Search for new targets for the treatment of cerebrovascular pathology: nuclear receptors PPARgamma and LXR; Tolllike receptors; cannabinoid receptors. ii) Innate immunity and stroke. iii) Cerebral ischemic tolerance. iv) Hemorrhagic transformation. v) Search for diagnostic and prognostic markers of cerebrovascular pathology. vi) Neurorepair in stroke. vii) Multiparametric image of vascular competition in stroke.
Dentro de la patología neurovascular, las líneas principales desarrolladas en la UIN son las siguientes: i) Búsqueda de nuevas dianas para el tratamiento de la patología cerebrovascular: receptores nucleares PPARgamma y LXR; receptores Tolllike; receptores cannabinoides. ii) Inmunidad innata e ictus. iii) Tolerancia isquémica cerebral. iv) Transformación hemorrágica. v) Búsqueda de marcadores diagnósticos y pronósticos de la patología cerebrovascular. vi) Neurorreparación en el ictus. vii) Imagen multiparamétrica de la competencia vascular en el ictus.
Ignacio Lizasoain Hernández.
Professor in the Department of Pharmacology at the Faculty of Medicine of the Complutense University of Madrid (UCM), he graduated in Medicine and Surgery at the UCM in 1986, and obtained his doctorate in Medicine in 1992 (Extraordinary Prize).
Since 1986 he has held various positions as an FPI Fellow, Marie Curie Fellow, Assistant Doctor, Full Professor and, since 2007, Professor. He carried out post-doctoral stays at the Wellcome Foundation Ltd (Beckenham. United Kingdom) with Prof. Salvador Moncada from 1991 to 1994 and at Massachusetts General Hospital (Harvard Medical School, Boston, USA) with Prof. Eng H. Lo in 2010. He has also been External Examiner of Trinity College Dublin (Faculty of Pharmacy and Pharmaceutical Sciences. University of Dublin, Ireland) from 2008 to 2010.
He is currently or has been Principal Investigator of three international projects (Human Capital and Mobility EU, NIH USA, NATO), more than 20 national projects (SAF, FIS, RETICS), more than 15 regional and/or local projects (Community of Madrid), and several projects funded with private funds. As a result of his research activity, he has published numerous works in the field of neuroscience and neurological sciences, especially in the field of neurovascular research. Her scientific production includes more than 155 JCR articles that have received more than 9,000-13,000 citations, with an "h index" of 54/62 (Scopus/Google scholar, July-2018). The complete list of publications can be found at Scopus and Orcid (no. 0000-0002-6028-7379). He is also co-editor of 6 textbooks, co-author of more than 60 book chapters, co-inventor of 3 patents and co-director of 19 doctoral theses.
In the Complutense University he has been Director of the Department of Pharmacology of the Faculty of Medicine of the UCM (2006-2010), Academic Secretary of the same Department (2010-2015), Coordinator of the Campus of Excellence Moncloa UCM-UPM in 2010 and of the i-Health Cluster from 2009 to date. Vice-chancellor of Scientific Policy, Research and Doctorate since 2015. Finally, he is Co-director of the Neurovascular Research Unit of the UCM.
Jesús Miguel Pradillo Justo.
Lecturer in the Department of Pharmacology of the Faculty of Medicine of the Complutense University of Madrid (UCM). He took a degree in Biological Sciences at the UCM in 2000, and obtained his doctorate in Sciences in 2008 (Extraordinary Prize).
Since 2002 he has held various positions as a predoctoral fellow Complutense, Contracted Postdoctoral PICATA (Campus of International Excellence Moncloa), Contracted Postdoctoral Madrid + Vision - Marie Curie, Assistant Professor and since 2018, Contracted Professor Doctor. He has made international stays in 2006 as a predoctoral scholar at Trinity College (Pharmacy School, Dublin, Ireland) and as a postdoctoral researcher from 2009 to 2013 at the University of Manchester, United Kingdom.
His career as a researcher has focused on the study of different aspects related to cerebral ischemia. He has been Principal Investigator of three projects, one international (Investing in Success Program, University of Manchester, United Kingdom), one inter-university (Picata Project, Complutense University - Autonomous University of Madrid) and one European (Madrid + Advanced Felloships Vision, Community of Madrid - FP7-MSCA-COFUND). He has also been a team member and collaborator in 16 national or regional projects (SAF, FIS, RETICS, Comunidad de Madrid).
Carolina Peña Martínez.
Degree in Psychology from the Complutense University of Madrid, specialized in the areas of Clinical Neuropsychology, as well as in Neuroscience through the realization of two masters in ITEAP and the Complutense University of Madrid, respectively. She is currently a member of the UIN as a predoctoral contract through the Aid for predoctoral contracts for research staff in training granted by the Ministry of Education, Social Policy and Sport during the academic year 2015/2016 for the completion of the doctoral thesis in the research group Neurovascular Research Unit (UIN).
Violeta Durán Laforet.
Graduated in Pharmacy from the Complutense University of Madrid. Victoria Eugenia Rodríguez García" Grade Award. Collaboration grant awarded by the Ministry of Education, Social Policy and Sport during the academic year 2015/2016 for the initiation of research in the research group Neurovascular Research Unit (UIN). Currently a member of the UIN in the capacity of predoctoral contract through the Aid for predoctoral contracts of research personnel in training (UCM-Harvard).
Alicia García Culebras.